KPV
Calming gut-health and inflammation research.
$89.00 18% off
KPV is the C-terminal tripeptide of alpha-MSH, studied for its anti-inflammatory signaling in the gut and skin. It is a favorite in gut-health and recovery research where a gentle profile is preferred.
What is KPV?
KPV is a tripeptide made up of lysine, proline and valine. It is the C-terminal fragment of alpha-melanocyte stimulating hormone, meaning it represents the final three amino acids of a much larger signalling molecule.
It is the quietest compound in the anti-inflammatory research category and arguably the most mechanistically interesting, which is an unusual combination and part of why researchers looking to buy KPV tend to arrive well informed.
KPV research applications
Published research focuses on inflammatory signalling, with much of the strongest work coming from gastrointestinal inflammation models rather than musculoskeletal ones. That origin is worth knowing, because KPV is frequently marketed for joints while the deeper literature sits in gut research.
Additional research areas include antimicrobial activity and wound healing, both less developed than the inflammatory work.
How KPV works
What makes KPV distinct is that the research describes it acting on specific intracellular inflammatory pathways rather than broadly suppressing the inflammatory response. Studies have examined its effect on NF-kB signalling, a central regulator of inflammatory gene expression.
That distinction matters for repair research specifically. Inflammation is the opening phase of healing rather than an obstacle to it, so a compound that modulates particular pathways is a meaningfully different proposition from one that blunts the whole response.
Buy KPV: specifications
| Specification | Detail |
|---|---|
| Compound | KPV (lysine-proline-valine) |
| Class | Alpha-MSH tripeptide fragment |
| Form | Lyophilized powder, sealed vial |
| Purity | Minimum 98%, verified by HPLC |
| Identity | Confirmed by mass spectrometry |
| Testing | Independent third-party laboratory, per batch |
| Origin | Shipped from the United States |
KPV in inflammation and recovery research
KPV is often studied alongside BPC-157 in repair contexts, where the reasoning is that one addresses the inflammatory environment while the other addresses vascularisation and tissue rebuilding. Studies of that specific combination are thin, so the pairing is better described as mechanistically reasonable than as demonstrated.
Our guide to peptides for recovery covers where inflammation research and repair research overlap and where they do not.
Reconstitution and handling
Supplied lyophilized. Reconstitute with bacteriostatic water, adding the diluent slowly down the vial wall and allowing it to dissolve without shaking. Bacteriostatic water is stocked separately.
Storage and stability
Store lyophilized vials sealed at minus 20 degrees Celsius, protected from light. Reconstituted solution requires refrigeration and has a shorter usable window. Avoid freeze and thaw cycling.
Certificate of analysis for every batch
Every KPV batch is tested by an independent US analytical laboratory for HPLC purity to a minimum of 98% and mass spectrometry identity, with the certificate published at our research page ahead of purchase.
Why researchers buy KPV from Healio
Third-party certificates published before you order, verified purity and identity, and US dispatch. KPV sits within the peptides for healing range.
KPV FAQ
What is KPV peptide used for in research?
Inflammatory signalling research, particularly in gastrointestinal models, plus antimicrobial and wound healing studies. Supplied for laboratory use only.
What does KPV stand for?
The three amino acids that make it up: lysine, proline and valine. It is the C-terminal fragment of alpha-melanocyte stimulating hormone.
How does KPV differ from general anti-inflammatories?
Research describes it acting on specific intracellular inflammatory pathways rather than suppressing the inflammatory response broadly, which is a different mechanism from conventional anti-inflammatory compounds.
What purity is Healio KPV?
Minimum 98% by HPLC with mass spectrometry identity confirmation from an independent laboratory, published per batch.
Research focus
- Gut-health research
- Inflammation response studies
- Skin and barrier models
- Digestive comfort research
Who it’s for
For researchers focused on
| Scientific name | Lys-Pro-Val |
|---|---|
| CAS number | 67727-97-3 |
| Molecular formula | C16H29N5O4 |
| Molecular weight | 355.4 g/mol |
| Sequence | Lys-Pro-Val |
| Purity | 98%+ (HPLC) |
| Form | Lyophilized powder |
| Appearance | White to off-white powder |
Store the lyophilized powder at -20u00b0C, protected from light. Brief exposure to room temperature during shipping does not affect stability.
After reconstitution, keep refrigerated at 2 to 8u00b0C and use within the research window. Do not freeze the reconstituted solution.
For laboratory research use only. Reconstitute with bacteriostatic water and handle with appropriate protective equipment.
