Peptides for Healing
4.9·392+ reviews

TB-500

Tissue repair and recovery research peptide.

$99.00 17% off

You save $49.90 (21%)2 × $94.05 instead of $119 each
In stock·ships within 24 hours

Bundle & Save

Third-Party TestedCOA with every batch
US-BasedShips from the USA
Free ShippingOn orders over $150

TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring peptide involved in cell migration and tissue repair. It is widely studied alongside BPC-157 in recovery research.

What is TB-500?

TB-500 is a synthetic fragment of thymosin beta-4, a naturally occurring protein involved in cell migration and tissue repair. It is not the full protein but the active region of it, which is why it appears in research as a practical laboratory material rather than a difficult-to-produce full-length molecule.

Thymosin beta-4 is one of the most abundant proteins in many cell types and is heavily involved in actin regulation, the protein scaffolding that lets cells change shape and move.

TB-500 research applications

Published research concentrates on soft tissue repair, cell migration, and actin sequestration. It is studied in tendon, ligament and muscle repair models, and frequently alongside BPC-157 on the reasoning that the two mechanisms address different stages of the same process.

The same caveat applies as across this category: the work is predominantly preclinical, and rodent musculoskeletal findings have a mixed record of transferring to human outcomes.

How TB-500 works

The core mechanism studied is actin binding. Actin is the structural protein that allows cells to migrate, and repair depends heavily on the right cells arriving at a damaged site and organising themselves once there. By influencing actin availability, thymosin beta-4 fragments appear to affect that migration process.

Secondary research areas include angiogenesis and inflammatory modulation, though these are less well characterised than the actin work.

TB-500 for sale: specifications

Specification Detail
Compound TB-500 (thymosin beta-4 fragment)
Class Synthetic peptide fragment
Form Lyophilized powder, sealed vial
Purity Minimum 98%, verified by HPLC
Identity Confirmed by mass spectrometry
Testing Independent third-party laboratory, per batch
Origin Shipped from the United States

TB-500 vs BPC-157

Property TB-500 BPC-157
Origin Thymosin beta-4 fragment Gastric protein fragment
Primary mechanism studied Cell migration, actin regulation Angiogenesis, vascularisation
Strongest research area Soft tissue repair Tendon repair, gut lining
Evidence type Mostly preclinical Mostly preclinical, larger volume

Both are available together in the RESTORE Stack.

Reconstitution and handling

Supplied lyophilized. Reconstitute with bacteriostatic water, adding the diluent slowly against the vial wall and allowing the powder to dissolve undisturbed. Do not shake. Bacteriostatic water is stocked separately.

Storage and stability

Store sealed lyophilized vials at minus 20 degrees Celsius, protected from light. Reconstituted material requires refrigeration and a shorter usable window. Do not freeze and thaw repeatedly.

Certificate of analysis for every batch

Independent third-party testing on every batch, covering HPLC purity to a minimum of 98% and mass spectrometry identity confirmation. Certificates are published openly at our research page before you order.

Why researchers buy TB-500 from Healio

Published batch certificates from an unaffiliated laboratory, verified purity and identity rather than claimed purity, and US dispatch with cold-chain handling. The full recovery range is under peptides for healing.

TB-500 FAQ

What is TB-500 used for in research?

Soft tissue repair models, cell migration studies, and actin regulation research, often in combination with BPC-157. Supplied for laboratory use only.

Is TB-500 the same as thymosin beta-4?

No. TB-500 is a synthetic fragment representing the active region of thymosin beta-4, not the complete protein.

Is TB-500 banned in sport?

Compounds in this class appear on anti-doping prohibited lists, which is a relevant consideration for competitive athletes and separate from laboratory research use. Check current WADA listings directly.

What testing does Healio TB-500 carry?

Independent third-party HPLC purity to a minimum of 98% with mass spectrometry identity confirmation, published per batch.

Research focus

  • Tissue repair research
  • Flexibility and recovery studies
  • Cell-migration models
  • Connective-tissue research

Who it’s for

For researchers focused on

HealingPeptides for Healing
Scientific nameThymosin Beta-4 Fragment
CAS number77591-33-4
Molecular formulaC212H350N56O78S
Molecular weight4963.4 g/mol
SequenceThymosin Beta-4 (43 residues)
Purity98%+ (HPLC)
FormLyophilized powder
AppearanceWhite to off-white powder
Lyophilized

Store the lyophilized powder at -20u00b0C, protected from light. Brief exposure to room temperature during shipping does not affect stability.

After reconstitution

After reconstitution, keep refrigerated at 2 to 8u00b0C and use within the research window. Do not freeze the reconstituted solution.

Handling

For laboratory research use only. Reconstitute with bacteriostatic water and handle with appropriate protective equipment.

For research use only. This product is intended strictly for laboratory research and is not for human or veterinary use, consumption, or diagnostic purposes. It is not a drug, supplement, food, or cosmetic, and no statements have been evaluated by the FDA. By purchasing, you confirm you are a qualified researcher or educational institution and will handle this material in accordance with all applicable laws.