SS-31

What is SS-31?

SS-31, also known as elamipretide, is a synthetic tetrapeptide designed to concentrate in the inner mitochondrial membrane. It has the most conventional pharmaceutical development history of any compound in the mitochondrial research category, having moved through formal clinical trial programmes for mitochondrial disease.

That development record is what separates it from most of the peptide market. It is a compound with real trial infrastructure behind it rather than a promising preclinical story.

SS-31 research applications

Research centres on mitochondrial function, cardiolipin interaction, and cellular energy production. It appears in both mitochondrial disease research and in ageing research, since mitochondrial decline is one of the named hallmarks of biological ageing.

One important qualification for anyone reading the trial data: those studies examined patient populations with diagnosed mitochondrial dysfunction, not healthy subjects. Reasoning from one to the other is plausible and remains an inference.

How SS-31 works

Cardiolipin is a phospholipid found almost exclusively in the inner mitochondrial membrane. It holds the components of the electron transport chain in the spatial arrangement that makes energy production efficient, and it degrades under oxidative stress and with age.

SS-31 is engineered to associate with cardiolipin rather than acting as a general free radical scavenger. That targeting is the mechanism: rather than mopping up oxidative damage broadly, it concentrates where the structural problem is.

SS-31 for sale: specifications

SS-31 vs MOTS-c

Both concern mitochondria and they arrive from opposite directions. SS-31 is a synthetic compound engineered to target a specific membrane phospholipid. MOTS-c is a naturally occurring peptide encoded in mitochondrial DNA that signals outward to the rest of the cell. SS-31 has the more formal clinical record; MOTS-c has the more unusual biology.

Both appear in our guide to the best peptides for energy and in our anti-aging peptide research guide.

Reconstitution and handling

Supplied lyophilized. Reconstitute with bacteriostatic water, adding the diluent slowly against the inside wall of the vial and allowing the powder to dissolve without agitation. Do not shake. Bacteriostatic water is stocked separately.

Storage and stability

Store sealed lyophilized vials at minus 20 degrees Celsius, protected from light. Reconstituted solution requires refrigeration and a shorter usable window. Avoid repeated freeze and thaw cycles.

Certificate of analysis for every batch

Every SS-31 batch is verified by an independent US analytical laboratory, with purity quantified by HPLC to a minimum of 98% and identity confirmed by mass spectrometry. Certificates are published at our research page before purchase.

Why researchers buy SS-31 from Healio

Independent verification published in advance rather than supplied on request, minimum 98% purity, mass spectrometry identity confirmation, and US dispatch. SS-31 sits in both peptides for energy and anti-aging peptides.

SS-31 FAQ

What is SS-31 used for in research?

Mitochondrial function studies, cardiolipin interaction research, and cellular energy production work. Supplied as a laboratory research material only.

Is SS-31 the same as elamipretide?

Yes, elamipretide is the development name for the same compound.

How does SS-31 differ from a general antioxidant?

It is engineered to associate with cardiolipin in the inner mitochondrial membrane rather than scavenging free radicals throughout the cell, which is a targeted rather than a broad mechanism.

What purity is Healio SS-31?

Minimum 98% by HPLC with mass spectrometry identity confirmation from an independent laboratory, published per batch.