PT-141

What is PT-141?

PT-141, also called bremelanotide, is a synthetic peptide that acts on melanocortin receptors. It is a derivative of melanotan II, developed after researchers observed effects during unrelated work on that compound.

It is one of a small number of peptides with research conducted specifically in women rather than extrapolated from male-dominant study populations, which is rare enough in this field to be worth noting.

PT-141 research applications

Published research concerns melanocortin receptor signalling and sexual response, with studies conducted in both male and female populations. Unlike compounds acting on the vascular system, the research on PT-141 concerns central nervous system pathways.

That mechanistic difference is the main reason it is studied separately from the more familiar vascular-acting compounds in this area.

How PT-141 works

The research describes activity at melanocortin receptors, particularly MC4R, which are involved in a range of central nervous system functions. This is a signalling pathway in the brain rather than a peripheral circulatory mechanism.

The melanocortin system is also involved in appetite regulation and inflammatory signalling, which is why fragments of related molecules, such as KPV, appear in entirely different research categories.

Buy PT-141: specifications

PT-141 in women's wellness research

PT-141 and kisspeptin-10 are the two compounds in the Healio catalog with genuinely female-focused research behind them. They act through different systems: PT-141 on melanocortin receptors, kisspeptin upstream in the reproductive hormone cascade.

Both sit in the women's wellness peptides range, and both feature in our guide to the best peptides for women.

Reconstitution and handling

Supplied lyophilized. Reconstitute with bacteriostatic water, adding the diluent slowly down the vial wall and allowing it to dissolve without shaking. Bacteriostatic water is stocked separately.

Storage and stability

Store sealed lyophilized vials at minus 20 degrees Celsius, protected from light. Reconstituted solution requires refrigeration and a shorter usable window. Avoid repeated freeze and thaw cycles.

Certificate of analysis for every batch

Independent third-party HPLC purity to a minimum of 98% and mass spectrometry identity confirmation on every batch, published at our research page before purchase.

Why researchers buy PT-141 from Healio

Published certificates from an unaffiliated laboratory, verified purity and identity, and US dispatch from a catalog built around research relevant to women.

PT-141 FAQ

What is PT-141 used for in research?

Melanocortin receptor signalling research and studies of sexual response pathways in the central nervous system. Supplied as a laboratory research material only, and not for human use.

Is PT-141 the same as bremelanotide?

Yes, bremelanotide is the development name for the same compound.

How does PT-141 differ from vascular-acting compounds?

The research concerns central nervous system melanocortin pathways rather than peripheral circulation, which is a fundamentally different mechanism.

What purity is Healio PT-141?

Minimum 98% by HPLC with mass spectrometry identity confirmation from an independent laboratory, published per batch.